The ANC/PNC Collective was created to innovate on interventions and service delivery approaches, test effectiveness of new tools, and ensure a coordinated, robust approach to data collection and analysis. Partnering with KEMRI in Kenya, CMC-Vallore in India, and RTI, HaSET will develop and test 1) models to predict risk and understand mechanisms of causality, 2) interventions to improve health outcomes, and 3) approaches to addressing intractable challenges across the maternal and newborn health continuum of care. We will be constructing a high-dimensional longitudinal clinical dataset that can support multiple analytical methods in biostatistics, epidemiology, and machine learning.